While my personal best wheel is a pack-3 pick-9 Polluted Delta, were talking about a different kind of Magic wheel
Though this also means that decks cannot be built in the same way as is the norm with other TCGs, it means that despite an expanding pool of cards, drawn from numerous, unusual factions you can never be certain what will lurk in a Keyforge pack
In Garruk's Wake + Plague Wind While Plague Wind and In Garruk's Wake do essentially the same thing, the latter kills planeswalkers so it makes it 99% strictly better (minus the regeneration clause)
Brimaz, Blight of Oreskos triggers each time you cast another Phyrexian creature spell, while Essence of Orthodoxy triggers when those Phyrexians enter the battlefield, making an excellent duo
Scolipede is one card release away from a decent power boost
Rakdos Charm is the perfect antidote to this kind of problem (although not the specifically the Moat one...), it can deal with a selection of troublesome things while remaining useful outside of this scope and perfectly maindeckable without fear of having dead cards or losing much consistency