At the cost of two mana and two sacrificed Humans, its controller can destroy a target creature with a power of two or greater, with a chance of removing an opponent's potentially game-winning creature from play
There are a number of ways the calculate or estimate this more specifically, but a quick rule of thumb is that basic mana should make up approximately one-third of their Magic: The Gathering deck, or 20 to 24 cards in a 60-card deck
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That means that unless it eats removal, counters decks, infect decks, and Superfriends decks will have a 7/5 in play on turn three that can do what Atraxa does up to four times a turn cycle
We can easily discount Pramikon
Its yet to cement itself in the metagame, only featuring as a sideboard card in the Top 8 of Worlds (in Golgari) yet its also showing up in builds of Esper Control