Yes, of course it can
It could be pesky enough that it will force opponents to remove it as soon as it comes in
Skithiryx, the Blight Dragon (Venom, King in Black) (MAR) $45 Skithiryx, the Blight Dragon jumped from a bulky rare to a Commander staple and valuable card thanks to its ability to infect and kill a player quickly
If you've tried to collect Pokmon cards recently, then you'll know that it's become quite the lucrative hobby, with the excessive demand and profit potential of getting those few rare cards turning it into a bit of an expensive exercise
Its also a card that needed a reprint, seeing as its very popular in Commander decks, even as a white commander
However, the threat was still far from over, and fearing the restraints breaking, the allied forces, with advice from Kerykeion, urged Shurit, Strategist of Nekroz to use the spiritual power of the 3 Ice Barrier dragons within himself to create a seal, freezing El Shaddoll Shekhinaga in place and completely incapacitating it